RA5 PAPER: Harnessing CRISPR-Cas

Harnessing CRISPR-Cas for oomycete genome editing

September 2023

Vink JNA, Hayhurst M, Gerth ML. 2023. Harnessing CRISPR-Cas for oomycete genome editing. Trends in Microbiology 31(9): 947 - 958.

ABSTRACT

Advances in CRISPR-Cas technologies (a genome editing tool) are being used to illuminate the biology of oomycetes, which ultimately can guide the development of tools for managing oomycete diseases. This paper also discusses some of the challenges to applying CRISPR-Cas in oomycetes and potential ways to overcome them.

KEYWORDS

CRISPR; genome editing; oomycetes; Phytophthora; stramenopiles