@prefix dcat: . @prefix dct: . @prefix foaf: . @prefix xsd: . a dcat:Dataset ; dct:description """#Tranche1: Project 2.7#\r \r ###Selected native plant extracts may be able to attract and kill the spores of *Phytophthora agathidicida* – the pathogen causing kauri dieback, according to researchers.##\r \r This project aims to find disease-fighting science solutions to protect New Zealand’s kauri forests through combining biochemical research with mātauranga Māori (Māori knowledge). The project is helping BioHeritage achieve its goal of creating a world-class biosecurity system for Aotearoa New Zealand.\r \r **Project Leader**\r \r - Monica Gerth, Victoria, University of Wellington""" ; dct:identifier "1335f5a7-ea3a-4f5a-b040-dc46989af8c1" ; dct:issued "2024-07-09T04:43:49.283042"^^xsd:dateTime ; dct:modified "2024-07-31T01:38:02.897679"^^xsd:dateTime ; dct:publisher ; dct:title "Stopping Kauri Dieback in its Tracks" ; dcat:distribution , , . a dcat:Distribution ; dct:description """###High-throughput chemical screening identifies compounds that inhibit different stages of the *Phytophthora agathidicida* and *Phytophthora cinnamomi* life cycles###\r \r **July 2017**\r \r **Lawrence SA, Armstrong CB, Patrick WM, Gerth ML 2017. [High-throughput chemical screening identifies compounds that inhibit different stages of the *Phytophthora agathidicida* and *Phytophthora cinnamomi* life cycles](https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2017.01340/pdf?isPublishedV2=false). Front Microbiol 8: 1340.**\r \r **ABSTRACT**\r \r Here, we have screened over 100 compounds for their anti-oomycete activity, as a potential first step toward identifying new control strategies. Our screening identified eight compounds that showed activity against both *Phytophthora* species. These included five antibiotics, two copper compounds and a quaternary ammonium cation. These compounds were tested for their inhibitory action against three stages of the *Phytophthora* life cycle: mycelial growth, zoospore germination, and zoospore motility.\r \r **KEYWORDS**\r \r oomycetes, *Agathis australis*, kauri dieback, avocado root rot, phenotype microarray, zoospore, high-throughput screening""" ; dct:issued "2024-07-09T04:49:47.265541"^^xsd:dateTime ; dct:modified "2024-07-09T04:49:47.265541"^^xsd:dateTime ; dct:title "PAPER: Compounds that Inhibit Phytophthora agathidicida & P. cinnamomi" ; dcat:accessURL . a dcat:Distribution ; dct:description """###*Phytophthora agathidicida*: research progress, cultural perspectives and knowledge gaps in the control and management of kauri dieback in New Zealand###\r \r **October 2019**\r \r **Bradshaw RE, Bellgard SE, Black A, Burns BR, Gerth ML, McDougal RL, Scott PM, Waipara NW, Weir BS, Williams NM and others 2020. [*Phytophthora agathidicida*: research progress, cultural perspectives and knowledge gaps in the control and management of kauri dieback in New Zealand](https://bsppjournals.onlinelibrary.wiley.com/doi/epdf/10.1111/ppa.13104). Plant Pathology 69(1): 3-16.**\r \r **ABSTRACT**\r \r Kauri (*Agathis australis*), which is one of the world's largest and longest-living conifer species, is under threat from a root and collar dieback disease caused by the oomycete pathogen *Phytophthora agathidicida*. The noted incidence of kauri dieback has increased in the past decade, and even trees >1000 years old are not immune. This disease has profound effects on both forest ecosystems and human society, particularly indigenous Māori, for whom kauri is a taonga or treasure of immense significance. This review brings together existing scientific knowledge about the pathogen and the devastating disease it causes, as well as highlighting important knowledge gaps and potential approaches for disease management. The life cycle of *P. agathidicida* is similar to those of other soilborne *Phytophthora* pathogens, with roles for vegetative hyphae, zoospores and oospores in the disease. However, there is comparatively little known about many aspects of the biology of *P. agathidicida*, such as its host range and disease latency, or about the impact on the disease of abiotic and biotic factors such as soil health and co-occurring *Phytophthora* species. This review discusses current and emerging tools and strategies for surveillance, diagnostics and management, including a consideration of genomic resources, and the role these play in understanding the pathogen and how it causes this deadly disease. Key aspects of indigenous Māori knowledge, which include rich ecological and historical knowledge of kauri forests and a holistic approach to forest health, are highlighted.\r \r **KEYWORDS**\r \r *Agathis australis*; disease impact; forest health; kauri dieback; oomycete; traditional indigenous knowledge\r """ ; dct:issued "2024-07-09T05:28:01.327482"^^xsd:dateTime ; dct:modified "2024-07-09T05:28:01.327482"^^xsd:dateTime ; dct:title "PAPER: Kauri dieback control: progress, perspectives, gaps." ; dcat:accessURL . a dcat:Distribution ; dct:description """###Matauranga-guided screening of New Zealand native plants reveals flavonoids from kanuka (*Kunzea robusta*) with anti-*Phytophthora* activity\r \r **August 2019**\r \r **Lawrence SA, Burgess EJ, Pairama C, Black A, Patrick WM, Mitchell I, Perry NB, Gerth ML 2019. [Matauranga-guided screening of New Zealand native plants reveals flavonoids from kanuka (*Kunzea robusta*) with anti-*Phytophthora* activity](https://www.tandfonline.com/doi/epdf/10.1080/03036758.2019.1648303?needAccess=true). Journal of the Royal Society of New Zealand 49: 137-154.**\r \r **ABSTRACT**\r \r Kauri is an ecologically important and culturally treasured tree species in Aotearoa New Zealand. It is under threat from the pathogenic oomycete *Phytophthora agathidicida*, which causes kauri dieback disease. We hypothesised that mātauranga Māori (Māori knowledge) of kauri forest health could be used to identify native plants that produce anti-*Phytophthora* compounds. We tested this hypothesis by using knowledge descended from Te Whare Wananga o Ngāpuhi to select and screen four native plants for activity against *P. agathidicida* and also *P. cinnamomi* (a broad host-range pathogen). Extracts of kānuka (*Kunzea robusta*) were active against various life cycle stages. Bioassay-directed isolation led to three flavanones, previously unreported from New Zealand *Kunzea*, as the main bioactives. These compounds have not previously been reported as having anti-*Phytophthora* activities. They inhibited *P. agathidicida* zoospore germination with IC50 values of 1.4–6.5 µg/mL, making them the most potent inhibitors reported against this stage of the life cycle. The three flavanones also inhibited zoospore motility at 2.5–5.0 µg/mL, and showed some inhibition of mycelial growth at 100 µg/mL. They were generally less active against *P. cinnamomi*. Overall, the results from this study emphasise the value of using mātauranga Māori in the response to kauri dieback.\r \r **KEYWORDS**\r \r Mātauranga Māori; oomycetes; *Phytophthora agathidicida*; kauri dieback; *Phytophthora cinnamomi*; anti-microbial; *Kunzea robusta*; kānuka; zoospore; flavonoid\r """ ; dct:issued "2024-07-09T05:44:12.634073"^^xsd:dateTime ; dct:modified "2024-07-09T05:44:12.634073"^^xsd:dateTime ; dct:title "PAPER: Kānuka flavonoids with anti-Phytophthora activity" ; dcat:accessURL . a foaf:Organization ; foaf:name "Challenge Inventory" .